Multi-stage bioengineering of a layered oesophagus with in vitro expanded muscle and epithelial adult progenitors
Abstract
A tissue engineered oesophagus could overcome limitations associated with oesophageal substitution. Combining decellularized scaffolds with patient-derived cells shows promise for regeneration of tissue defects. In this proof-of-principle study, a two-stage approach for generation of a bio-artificial oesophageal graft addresses some major challenges in organ engineering, namely: (i) development of multi-strata tubular structures, (ii)...
Paper Details
Title
Multi-stage bioengineering of a layered oesophagus with in vitro expanded muscle and epithelial adult progenitors
Published Date
Oct 16, 2018
Journal
Volume
9
Issue
1
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Notes
History