Original paper
A facile consensus ranking approach enhances virtual screening robustness and identifies a cell-active DYRK1α inhibitor
Abstract
Background: Virtual screening is vital for contemporary drug discovery but striking performance fluctuations are commonly encountered, thus hampering error-free use. Results and Methodology: A conceptual framework is suggested for combining screening algorithms characterized by orthogonality (docking-scoring calculations, 3D shape similarity, 2D fingerprint similarity) into a simple, efficient and expansible python-based consensus ranking...
Paper Details
Title
A facile consensus ranking approach enhances virtual screening robustness and identifies a cell-active DYRK1α inhibitor
Published Date
Oct 1, 2018
Journal
Volume
10
Issue
20
Pages
2411 - 2430
Citation AnalysisPro
You’ll need to upgrade your plan to Pro
Looking to understand the true influence of a researcher’s work across journals & affiliations?
- Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
- Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.
Notes
History