An approach to apply eco-friendly subcritical water oxidation method in the mineralization of the antibiotic ampicillin

Mineralization of ampicillin, a semi-synthetic β-lactam penicillin, was investigated in subcritical water medium in the presence of hydrogen peroxide. Optimisation of the employed method was performed by the central composite design of the response surface methodology. Effects of each independent variable such as temperature, treatment time, and concentration of the oxidizing agent and their co-effects on TOC removal percentages were evaluated....