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Interactions between Metal Oxides and Biomolecules: from Fundamental Understanding to Applications

Published on Nov 28, 2018in Chemical Reviews54.30
· DOI :10.1021/acs.chemrev.7b00660
Marion J. Limo4
Estimated H-index: 4
(NTU: Nottingham Trent University),
Anna Sola-Rabada4
Estimated H-index: 4
(NTU: Nottingham Trent University)
+ 4 AuthorsCarole C. Perry46
Estimated H-index: 46
(NTU: Nottingham Trent University)
Abstract
Metallo-oxide (MO)-based bioinorganic nanocomposites promise unique structures, physicochemical properties, and novel biochemical functionalities, and within the past decade, investment in research on materials such as ZnO, TiO2, SiO2, and GeO2 has significantly increased. Besides traditional approaches, the synthesis, shaping, structural patterning, and postprocessing chemical functionalization of the materials surface is inspired by strategies which mimic processes in nature. Would such materials deliver new technologies? Answering this question requires the merging of historical knowledge and current research from different fields of science. Practically, we need an effective defragmentation of the research area. From our perspective, the superficial accounting of material properties, chemistry of the surfaces, and the behavior of biomolecules next to such surfaces is a problem. This is particularly of concern when we wish to bridge between technologies in vitro and biotechnologies in vivo. Further, be...
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#1Naomi Kramer (BGU: Ben-Gurion University of the Negev)
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#1Graham E. Tilburey (NTU: Nottingham Trent University)H-Index: 3
#2Toby J. Blundell (NTU: Nottingham Trent University)
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