Increasing Dietary Fiber Intake Is Associated with a Distinct Esophageal Microbiome

Introduction: There is increasing evidence that the microbiome contributes to esophageal disease. Diet, especially fiber and fat intake, is a known potent modifier of the colonic microbiome, but its impact on the esophageal microbiome is not well described. We hypothesized that dietary fiber and fat intake would be associated with a distinct esophageal microbiome. Methods: We collected esophageal samples from 47 ambulatory patients scheduled to...