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References39
Newest
Published on Jun 22, 2018in British Journal of Sports Medicine11.64
Alessio Bricca2
Estimated H-index: 2
,
Carsten Bogh Juhl15
Estimated H-index: 15
(UCPH: University of Copenhagen)
+ 2 AuthorsEwa M. Roos63
Estimated H-index: 63
Objective To investigate the impact of knee joint loading exercise on articular cartilage in people at risk of, or with established, knee osteoarthritis (OA) by conducting a systematic review of randomised controlled trials (RCTs). Design We followed the Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines. Data sources We performed a literature search with no restriction on publication year or language in MEDLINE, EMBASE, CINAHL, the Cochrane Central Register of Control...
Published on Nov 1, 2018in Osteoarthritis and Cartilage4.88
Søren Thorgaard Skou15
Estimated H-index: 15
(University of Southern Denmark),
Alessio Bricca2
Estimated H-index: 2
(University of Southern Denmark),
Ewa M. Roos63
Estimated H-index: 63
(University of Southern Denmark)
Summary Objectives It is unknown if people with knee osteoarthritis (OA) who are already physically active benefit from exercise therapy. To study the impact of physical activity level on pain relief, post-intervention and 12 months following exercise therapy and education. Method The analyses included 12,796 patients with knee OA from the Good Life with osteoArthritis in Denmark (GLA:D ® ) program. GLA:D ® consists of 12 sessions of supervised neuromuscular exercise and two sessions of educatio...
Published on Dec 1, 2017in Osteoarthritis and Cartilage4.88
W. Wirth33
Estimated H-index: 33
,
David H. Hunter178
Estimated H-index: 178
(RNSH: Royal North Shore Hospital)
+ 4 AuthorsFelix Eckstein73
Estimated H-index: 73
Summary Objective To investigate the predictive and concurrent validity of magnetic resonance imaging (MRI)-based cartilage thickness change between baseline (BL) and year-two (Y2) follow-up (predictive validity) and between Y2 and Y4 follow-up (concurrent validity) for symptomatic and radiographic knee osteoarthritis (OA) progression during Y2→Y4. Methods 777 knees from 777 Osteoarthritis Initiative (OAI) participants (age: 61.3 ± 9.0 years, BMI: 30.1 ± 4.8 kg/m 2 ) with Kellgren Lawrence (KL) ...
Published on Aug 1, 2017in Arthritis Care and Research4.53
Adam G Culvenor12
Estimated H-index: 12
(La Trobe University),
David T. Felson135
Estimated H-index: 135
(BU: Boston University)
+ 4 AuthorsFelix Eckstein73
Estimated H-index: 73
Objective. To determine whether lower thigh muscle specific strength increases risk of incident radiographic knee osteoarthritis (RKOA), and whether there exists a sex-specific relationship between thigh muscle specific strength and BMI. Methods. 161 Osteoarthritis Initiative participants (62% female) with incident RKOA (Kellgren-Lawrence grade 0/1 at baseline, developing an osteophyte and joint space narrowing grade ≥1 by year 4) were matched to 186 controls (58% female) without incident RKOA. ...
Published on May 1, 2017in American Journal of Sports Medicine6.09
Kate A. Timmins3
Estimated H-index: 3
(University of Nottingham),
R. Leech1
Estimated H-index: 1
(University of Nottingham)
+ 1 AuthorsKimberley L. Edwards11
Estimated H-index: 11
(University of Nottingham)
Background:Osteoarthritis (OA) is a chronic condition characterized by pain, impaired function, and reduced quality of life. A number of risk factors for knee OA have been identified, such as obesity, occupation, and injury. The association between knee OA and physical activity or particular sports such as running is less clear. Previous reviews, and the evidence that informs them, present contradictory or inconclusive findings.Purpose:This systematic review aimed to determine the association be...
Published on Apr 1, 2017in The Journal of Rheumatology3.63
Adam El Mongy Jørgensen1
Estimated H-index: 1
(UCPH: University of Copenhagen),
Michael Kjaer90
Estimated H-index: 90
,
Katja M. Heinemeier24
Estimated H-index: 24
Objective The morphology of articular cartilage (AC) enables painless movement. Aging and mechanical loading are believed to influence development of osteoarthritis (OA), yet the connection remains unclear. Methods This narrative review describes the current knowledge regarding this area, with the literature search made on PubMed using appropriate keywords regarding AC, age, and mechanical loading. Results Following skeletal maturation, chondrocyte numbers decline while increasing senescence occ...
Published on Feb 1, 2017in Seminars in Arthritis and Rheumatism5.07
Felix Eckstein73
Estimated H-index: 73
,
R. Buck19
Estimated H-index: 19
,
W. Wirth33
Estimated H-index: 33
Abstract Objective The metric accepted by regulatory bodies for determining structural progression in clinical trials of knee osteoarthritis (OA) remains change in radiographic joint space width in the medial femorotibial compartment. However, magnetic resonance imaging has revealed that cartilage loss is spatially heterogeneous, and that it is enigmatic which knee will lose cartilage at which location. Whereas previous reviews have focused on imaging in general, the purpose of this particular p...
Published on Feb 1, 2017in Osteoarthritis and Cartilage4.88
David J. Saxby6
Estimated H-index: 6
(Griffith University),
David G. Lloyd48
Estimated H-index: 48
(Griffith University)
Inappropriate biomechanics, namely wear-and-tear, has been long believed to be a main cause of osteoarthritis (OA). However, this view is now being re-evaluated, especially when examined alongside mechanobiology and new biomechanical studies. These are multiscale experimental and computational studies focussing on cell- and tissue-level mechanobiology through to organ- and whole-body-level biomechanics, which focuses on the biomechanical and biochemical environment of the joint tissues. This rev...
Published on Nov 1, 2016in Osteoarthritis and Cartilage4.88
Ola Olsson1
Estimated H-index: 1
,
A. Isacsson1
Estimated H-index: 1
+ 1 AuthorsR. Frobell21
Estimated H-index: 21
(Lund University)
Summary Objective In patients with traumatic knee distorsion and hemarthrosis, to investigate the panorama of structural injury, as visualized on magnetic resonance imaging (MRI). Design Cohort study of 1145 consecutive patients with traumatic knee distorsion who underwent MRI within median 8 days after injury. We present structural injury as visualized on MRI in relation to age, sex and activity at injury. Population based gender specific annual incidences of common structural injuries were cal...
Published on Nov 1, 2016in Osteoarthritis and Cartilage4.88
R. Kwee2
Estimated H-index: 2
(JHUSOM: Johns Hopkins University School of Medicine),
W. Wirth33
Estimated H-index: 33
+ 3 AuthorsShadpour Demehri13
Estimated H-index: 13
(JHUSOM: Johns Hopkins University School of Medicine)
Summary Objective To assess the association between physical activity and cartilage damage progression in medial tibiofemoral compartment (MTFC) using 2-year follow-up magnetic resonance imaging (MRI) in subjects with denuded areas of subchondral bone (dABs) at the central weight-bearing medial femur (cMF) at baseline MRI examination. Methods One hundred subjects from the Osteoarthritis Initiative (OAI) progression cohort with dABs at the cMF at 3T MRI at baseline (51% men; mean age 62.2 years, ...
Cited By1
Newest
Published on May 1, 2019in Gait & Posture2.41
Jocelyn F. Hafer5
Estimated H-index: 5
(UMass: University of Massachusetts Amherst),
Jocelyn F. Hafer (UMass: University of Massachusetts Amherst)+ 0 AuthorsKatherine A. Boyer12
Estimated H-index: 12
(UMass: University of Massachusetts Amherst)
Abstract Background Knee osteoarthritis (OA) is a highly prevalent disease leading to mobility disability in the aged that could, in part, be initiated by age-related alterations in knee mechanics. However, if and how knee mechanics change with age remains unclear. Research question What are the impacts of age and physical activity (PA) on biomechanical characteristics that can affect the loading environment in the knee during gait? Methods Three groups (n = 20 each, 10 male and 10 female) of he...