Reduced PSA Surveillance Following SBRT for Favorable Prostate Cancer Decreases the Incidence of Anxiety-Promoting Benign PSA Bounces without Limiting the Early Detection of Biochemical Failures

Stereotactic Body Radiation Therapy (SBRT) has emerged as a convenient, effective, and safe treatment option for favorable risk prostate cancer. A benign Prostate-Specific Antigen (PSA) bounce is a temporary elevation of PSA above prior values. These PSA variations are common following ultra-hypofractionated SBRT (30-40%) and frequently lead to patient anxiety. In this report, we compare our standard PSA surveillance schedule with an alternative...