Benzene Exposure Induces Insulin Resistance in Mice
Abstract
Benzene is a ubiquitous pollutant associated with hematotoxicity but its metabolic effects are unknown. We sought to determine if and how exposure to volatile benzene impacted glucose handling. We exposed wild type C57BL/6 mice to volatile benzene (50 ppm × 6 h/day) or HEPA-filtered air for 2 or 6 weeks and measured indices of oxidative stress, inflammation, and insulin signaling. Compared with air controls, we found that mice inhaling benzene...
Paper Details
Title
Benzene Exposure Induces Insulin Resistance in Mice
Published Date
Oct 22, 2018
Journal
Volume
167
Issue
2
Pages
426 - 437
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