Novel protein science enabled by total chemical synthesis

Chemical synthesis is a well‐established method for the preparation in the research laboratory of multiple‐tens‐of‐milligram amounts of correctly folded, high purity protein molecules. Chemically synthesized proteins enable a broad spectrum of novel protein science. Racemic mixtures consisting of d ‐protein and l ‐protein enantiomers facilitate crystallization and determination of protein structures by X‐ray diffraction. d ‐Proteins enable the...