Sleep/Wake Disruption in a Mouse Model of BLOC-1 Deficiency
Abstract
Mice lacking a functional Biogenesis of Lysosome-related Organelles Complex 1 (BLOC-1), such as those of the pallid line, display cognitive and behavioural impairments reminiscent of those presented by individuals with intellectual and developmental disabilities. Although disturbances in the sleep/wake cycle are commonly lamented by these individuals, the underlying mechanisms, including the possible role of the circadian timing system, are...
Paper Details
Title
Sleep/Wake Disruption in a Mouse Model of BLOC-1 Deficiency
Published Date
Nov 15, 2018
Journal
Volume
12
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