Cardiovascular disease models: A game changing paradigm in drug discovery and screening
Abstract
Cardiovascular disease is the leading cause of death worldwide. Although investment in drug discovery and development has been sky-rocketing, the number of approved drugs has been declining. Cardiovascular toxicity due to therapeutic drug use claims the highest incidence and severity of adverse drug reactions in late-stage clinical development. Therefore, to address this issue, new, additional, replacement and combinatorial approaches are needed...
Paper Details
Title
Cardiovascular disease models: A game changing paradigm in drug discovery and screening
Published Date
Apr 1, 2019
Journal
Volume
198
Pages
3 - 26
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