Minimizing Membrane Arachidonic Acid Content as a Strategy for Controlling Cancer: A Review
Abstract
Many cancers and pre-cancerous lesions convert membrane-bound arachidonic acid (AA) to eicosanoids that promote the survival, growth, and spread of cancer. In contrast, the long-chain omega-3s eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) can competitively inhibit AA’s interaction with the enzymes that give rise to eicosanoids, while acting as precursors for alternative eicosanoids which oppose cancer development and growth. Hence,...
Paper Details
Title
Minimizing Membrane Arachidonic Acid Content as a Strategy for Controlling Cancer: A Review
Published Date
Aug 18, 2018
Journal
Volume
70
Issue
6
Pages
840 - 850
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