Self-nanoemulsifying system improves oral absorption and enhances anti-acute myeloid leukemia activity of berberine

Volume: 16, Issue: 1
Published: Oct 5, 2018
Abstract
Recently, we found that berberine (BBR) exerts anti-acute myeloid leukemia activity, particularly toward high-risk and relapsed/refractory acute myeloid leukemia MV4-11 cells in vitro. However, the poor water solubility and low bioavailability observed with oral BBR administration has limited its clinical use. Therefore, we design and develop a novel oil-in-water self-nanoemulsifying system for BBR (BBR SNE) to improve oral bioavailability and...
Paper Details
Title
Self-nanoemulsifying system improves oral absorption and enhances anti-acute myeloid leukemia activity of berberine
Published Date
Oct 5, 2018
Volume
16
Issue
1
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