Integrative network and brain expression analysis reveals mechanistic modules in ataxia

Volume: 56, Issue: 5, Pages: 283 - 292
Published: Dec 27, 2018
Abstract
Background Genetic forms of ataxia are a heterogenous group of degenerative diseases of the cerebellum. Many causative genes have been identified. We aimed to systematically investigate these genes to better understand ataxia pathophysiology. Methods A manually curated catalogue of 71 genes involved in disorders with progressive ataxias as a major clinical feature was subjected to an integrated gene ontology, protein network and brain gene...
Paper Details
Title
Integrative network and brain expression analysis reveals mechanistic modules in ataxia
Published Date
Dec 27, 2018
Volume
56
Issue
5
Pages
283 - 292
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