Can maternal treatment with metformin during gestation and lactation cause metabolic and cardiovascular disorders in rat offspring?
Volume: 126, Issue: 3, Pages: 276 - 281
Published: Sep 29, 2018
Abstract
Objective: The aim was to evaluate if maternal treatment with metformin (MET) during pregnancy and lactation could be safe for metabolic and cardiovascular parameters of adult male and female offspring.Materials and methods: Wistar female rats were treated with MET (293 mg/kg/d) or tap water, by gavage during gestation (METG or CTRG) or gestation and lactation (METGL or CTRGL).Results: At 75 days of life, male and female MET offspring presented...
Paper Details
Title
Can maternal treatment with metformin during gestation and lactation cause metabolic and cardiovascular disorders in rat offspring?
Published Date
Sep 29, 2018
Volume
126
Issue
3
Pages
276 - 281
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