A transgenic minipig model of Huntington's disease shows early signs of behavioral and molecular pathologies

Published: Jan 1, 2018
Abstract
Huntington's disease (HD) is a monogenic, progressive, neurodegenerative disorder with currently no available treatment. The Libechov transgenic minipig model for HD (TgHD) displays neuroanatomical similarities to humans and exhibits slow disease progression and therefore more powerful compared to available mouse models for the development of therapy. The phenotypic characterization of this model is still ongoing, and it is essential to validate...
Paper Details
Title
A transgenic minipig model of Huntington's disease shows early signs of behavioral and molecular pathologies
Published Date
Jan 1, 2018
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