Fisetin is a senotherapeutic that extends health and lifespan
Abstract
Senescence is a tumor suppressor mechanism activated in stressed cells to prevent replication of damaged DNA. Senescent cells have been demonstrated to play a causal role in driving aging and age-related diseases using genetic and pharmacologic approaches. We previously demonstrated that the combination of dasatinib and the flavonoid quercetin is a potent senolytic improving numerous age-related conditions including frailty, osteoporosis and...
Paper Details
Title
Fisetin is a senotherapeutic that extends health and lifespan
Published Date
Oct 1, 2018
Journal
Volume
36
Pages
18 - 28
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Notes
History