Identification of hepatotoxicity and renal dysfunction of pyrene in adult male rats
Abstract
Polycyclic aromatic hydrocarbons (PAHs) are a group of persistent organic pollutants primarily formed from the incomplete combustion of carbonaceous materials, and have adverse effects on human health. In this study, we investigated whether pyrene, a PAH consisting of 4 fused benzene rings, has adverse effects on rat. Adult male Sprague‐Dawly rats were treated daily by oral gavage with vehicle (corn oil) or pyrene at doses of 375, 750, 1500, or...
Paper Details
Title
Identification of hepatotoxicity and renal dysfunction of pyrene in adult male rats
Published Date
Sep 21, 2018
Journal
Volume
33
Issue
12
Pages
1304 - 1311
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