Glucagon-like peptide-1 receptor action in the vasculature
Abstract
Glucagon-like peptide-1 receptor (GLP-1R) agonists augment insulin secretion and are thus used clinically to improve glycemia in subjects with type 2 diabetes (T2D). As recent data reveal marked improvements in cardiovascular outcomes in T2D subjects treated with the GLP-1R agonists liraglutide and semaglutide in the LEADER and SUSTAIN-6 clinical trials respectively, there is growing interest in delineating the mechanism(s) of action for GLP-1R...
Paper Details
Title
Glucagon-like peptide-1 receptor action in the vasculature
Published Date
Jan 1, 2019
Journal
Volume
111
Pages
26 - 32
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