Laboratory assessment of folate (vitamin B₉) status

Folate (vitamin B 9 ) plays a crucial role in fundamental cellular processes, including nucleic acid biosynthesis, methyl group biogenesis and amino acid metabolism. The detection and correction of folate deficiency prevents megaloblastic anaemia and reduces the risk of neural tube defects. Coexisting deficiencies of folate and vitamin B 12 are associated with cognitive decline, depression and neuropathy. Folate deficiency and excess has also...