Review paper
Polygenic risk score for breast cancer in high-risk women.
Volume: 36, Issue: 15_suppl, Pages: 1508 - 1508
Published: May 20, 2018
Abstract
1508 Background: While assessment of genetic contribution to breast cancer (BC) risk was once limited to high-penetrance genes such as BRCA1/2, additional genes conferring two- to five-fold increased risks of BC, as well common SNPs with relative risks ranging 1.03-1.57, have recently been identified. Although several reports suggest that a score based on combined genotypes across a large number of SNPs may have substantial predictive value for...
Paper Details
Title
Polygenic risk score for breast cancer in high-risk women.
Published Date
May 20, 2018
Journal
Volume
36
Issue
15_suppl
Pages
1508 - 1508
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