Gender identity in patients with 5-alpha reductase deficiency raised as females

Background and objective 5-Alpha reductase type 2 deficiency (5-ARD) is a rare disorder of sex development. The lack of 5-alpha reductase, an enzyme that converts testosterone into dihydrotestosterone, results in external genitalia that may appear female, or predominantly male, albeit undervirilized, or, more often, ambiguous. Methods This study describes a series of patients with 5-ARD raised as female, focusing on aspects related to gender...