Two potent C4 and C4b nanobodies inhibiting the classical pathway of the complement system
Abstract
Status epilepticus (SE) is a prolonged and continuous seizure that lasts for at least 5 min. An episode of SE in a healthy system can lead to the development of spontaneous seizures and cognitive deficits which may be accompanied by hippocampal injury and microgliosis. Although the direct mechanisms underlying the SE-induced pathophysiology remain unknown, a candidate mechanism is hyperactivation of the classical complement pathway (C1q-C3...
Paper Details
Title
Two potent C4 and C4b nanobodies inhibiting the classical pathway of the complement system
Published Date
Oct 1, 2018
Journal
Volume
102
Pages
231 - 231
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