Multi-centre clinical study of cell-free DNA mutations in benign and malignant lung lesions.

e24036 Background: Cell-free circulating tumor DNA (ctDNA) for cancer detection drew significant clinical attention. Concordance of mutations in tumor tissue and ctDNA should be evaluated first. Methods: We designed andconducted a multi-center clinical trial at three (3) Tier A hospitals in China to recruit patients with occupying diseases of lung that will be treated by surgery. Patients with lung nodules or cancers of Stage I to III were...