Polypyridyl‐Based Copper Phenanthrene Complexes: A New Type of Stabilized Artificial Chemical Nuclease

The building of robust and versatile inorganic scaffolds with artificial metallo‐nuclease (AMN) activity is an important goal for bioinorganic, biotechnology, and metallodrug research fields. Here, a new type of AMN combining a tris‐(2‐pyridylmethyl)amine (TPMA) scaffold with the copper(II) N , N′ ‐phenanthrene chemical nuclease core is reported. In designing these complexes, the stabilization and flexibility of TPMA together with the prominent...