Parallels between Mammalian Mechanisms of Monoallelic Gene Expression

MAE systems have diverse biological roles, but show similarities in the underlying epigenetic mechanisms. Transcriptional events and non-coding RNAs are associated with the initiation of MAE. Differential modification and architectures of chromatin are also important in MAE. The different MAE systems found in mammals may have evolved from analogous ancestral processes. Different types of monoallelic gene expression are present in mammals, some...