Preconditioning contractions prevent the delayed onset of myofibrillar dysfunction after damaging eccentric contractions

Key points We examined the mechanisms underlying the positive effect of preconditioning contractions (PCs) on the recovery of muscle force after damaging eccentric contractions (ECCs). The mechanisms underlying the immediate force decrease after damaging ECCs differ from those causing depressed force with a few days’ delay, where reactive oxygen species (ROS) produced by invading immune cells play an important causative role. PCs counteracted...