Skin nerve α-synuclein deposits in a parkinsonian patient with heterozygous parkin mutation

α-Synuclein (α-syn) is the main pathological hallmark of Lewy body diseases, a group of diseases that includes idiopathic Parkinson's disease (iPD), Dementia with Lewy body (DLB), and Multiple System Atrophy. α-Syn forms pathological aggregates that can be detected in central and peripheral nervous system [ [4] Donadio V. Incensi A. Rizzo G. et al. A new potential biomarker for dementia with Lewy bodies: skin nerve α-synuclein deposits....