Matrix metalloproteinase-10 deficiency delays atherosclerosis progression and plaque calcification

Background and aims Matrix metalloproteinases (MMPs) have been implicated in atherosclerosis and vascular calcification. Among them, we reported that MMP10 is present in human atheroma, associated with atherosclerosis. However, it remains unclear whether MMP10 is involved in atherogenesis and vascular calcification. Methods MMP10 was measured in serum from patients with subclinical atherosclerosis and analyzed in carotid endarterectomies by...