Predictive biomarkers of ipilimumab toxicity in metastatic melanoma.
Volume: 35, Issue: 15_suppl, Pages: 9559 - 9559
Published: May 20, 2017
Abstract
9559 Background: There are no predictive biomarkers of ipilimumab (IPI) toxicity. Of metastatic melanoma (MM) patients (pts) receiving IPI (3mg/kg), 35% require systemic therapies to treat immune-related adverse events (irAEs) and 20% must terminate treatment (Horvat et al., JCO 2015). Here we tested the hypothesis that a pre-existing autoantibody (autoAb) profile is predictive of IPI irAEs. Methods: We measured autoAb levels in pre- and...
Paper Details
Title
Predictive biomarkers of ipilimumab toxicity in metastatic melanoma.
Published Date
May 20, 2017
Journal
Volume
35
Issue
15_suppl
Pages
9559 - 9559
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