The role of geospatial hotspots in the spatial spread of tuberculosis in rural Ethiopia: a mathematical model

Geospatial tuberculosis (TB) hotspots are hubs of TB transmission both within and across community groups. We aimed to quantify the extent to which these hotspots account for the spatial spread of TB in a high-burden setting. We developed spatially coupled models to quantify the spread of TB from geographical hotspots to distant regions in rural Ethiopia. The population was divided into three 'patches' based on their proximity to transmission...