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Role of post‐operative serum C‐reactive protein levels as a predictor of complications in upper gastrointestinal surgery

Published on Jan 1, 2019in Anz Journal of Surgery1.605
· DOI :10.1111/ans.14789
Christoph Späth (North Shore Hospital), Sanket Srinivasa17
Estimated H-index: 17
(North Shore Hospital)
+ 3 AuthorsJonathan B. Koea20
Estimated H-index: 20
(North Shore Hospital)
Abstract
  • References (31)
  • Citations (0)
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References31
Newest
#1Alexandra C. Gordon (Christchurch Hospital)H-Index: 1
#2Andrea J. Cross (Christchurch Hospital)H-Index: 4
Last. Ross H. Roberts (Christchurch Hospital)H-Index: 5
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10 CitationsSource
#1Théophile Guilbaud (AMU: Aix-Marseille University)H-Index: 3
#2David Jérémie Birnbaum (AMU: Aix-Marseille University)H-Index: 5
Last. Vincent Moutardier (AMU: Aix-Marseille University)H-Index: 30
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Background Postoperative pancreatic fistula and pancreas-specific complications have a significant influence on patient management and outcomes after pancreatoduodenectomy. The aim of the study was to assess the value of serum C-reactive protein on the postoperative day 1 as early predictor of pancreatic fistula and pancreas-specific complications.
1 CitationsSource
Background The association between postoperative inflammatory markers and risk of complications after pancreaticoduodenectomy (PD) is controversial. We sought to assess the diagnostic value of perioperative C-reactive protein (CRP) and procalcitonin (PCT) levels in the early identification of patients at risk for complications after PD.
9 CitationsSource
#1Stefan Buettner (Johns Hopkins University)H-Index: 16
#2Faiz Gani (Johns Hopkins University)H-Index: 17
Last. Timothy M. Pawlik (Johns Hopkins University)H-Index: 82
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Background Although previous reports have focused on factors at the hospital level to explain variations in postoperative outcomes, less is known regarding the effect of provider-specific factors on postoperative outcomes such as failure-to-rescue (FTR) and postoperative mortality. The current study aimed to quantify the relative contributions of surgeon and hospital volume on the volume–outcomes relationship among a cohort of patients undergoing liver resection. Methods Patients undergoing live...
35 CitationsSource
#1Litong Ji (HMU: Harbin Medical University)H-Index: 1
#2Tie Wang (HMU: Harbin Medical University)H-Index: 1
Last. Meizhuo Gao (HMU: Harbin Medical University)H-Index: 2
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Abstract Background/Aims The incidence of esophagogastric junction (EGJ) carcinoma has increased worldwide. The only curable strategy for EGJ carcinoma is surgery, whereas anastomotic leakage is the major complication after operations. We aimed to test whether the serum levels of C-reactive protein have the diagnostic value for anastomotic leakage after surgery for EGJ carcinoma. Methods In this study, we analyzed the values of CRP before and 5 continuous days after surgery in 97 EGJ carcinoma p...
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#1Swapnil D. Kachare (ECU: East Carolina University)H-Index: 8
#2Kendall R. Liner (ECU: East Carolina University)H-Index: 1
Last. Timothy L. Fitzgerald (ECU: East Carolina University)H-Index: 22
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Abstract Background Pancreatic surgery is complex with the potential for costly hospitalization. Methods A retrospective review of patients undergoing a pancreatic resection was performed. Results The median age of the study population was 64 years. Half of the cohort was female (51%), and the majority were white (62%). Most patients underwent a pancreaticoduodenectomy (PD) (69%). The pre-operative age-adjusted Charlson comorbidity index was zero for 36% ( n = 50), 1 for 31% ( n = 43) and ≥2 for...
8 CitationsSource
#1Neda Amini (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 18
#2Gaya Spolverato (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 31
Last. Timothy M. Pawlik (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 82
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Background We sought to evaluate trends in selection of high volume (HV) hospitals for pancreatic surgery, as well as examine trends in preoperative complications, mortality, and failure to rescue (FTR).
55 CitationsSource
#1Sandra H. Hoeboer (EUR: Erasmus University Rotterdam)H-Index: 3
#2A. B. Johan Groeneveld (EUR: Erasmus University Rotterdam)H-Index: 39
Last. Jasper van Bommel (EUR: Erasmus University Rotterdam)H-Index: 27
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Background Elective esophagectomy with gastric tube reconstruction carries a high risk for complications. Early and accurate diagnosis could improve patient management. Increased C-reactive protein (CRP) levels may be associated with any, surgical or infectious, complication and procalcitonin (PCT) specifically with infectious complications.
21 CitationsSource
#1Daniel J. KagedanH-Index: 6
#2Mahrosh Ahmed (Princess Margaret Cancer Centre)H-Index: 1
Last. Alice C. Wei (U of T: University of Toronto)H-Index: 16
view all 4 authors...
Background Enhanced recovery after surgery (ERAS) protocols have been shown to reduce hospital stay without compromising outcomes. Attempts to apply ERAS principles in the context of pancreatic surgery have generated encouraging results. A systematic review of the current evidence for ERAS following pancreatic surgery was conducted.
66 CitationsSource
#1Gaya Spolverato (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 31
#2Aslam Ejaz (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 24
Last. Timothy M. Pawlik (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 82
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Background The mechanisms that underlie the association between high surgical volume and improved outcomes remain uncertain. This study examined the impact of complications and failure to rescue patients from these complications on mortality following hepatic resection. Methods The Nationwide Inpatient Sample was used to identify patients who had liver surgery between 2000 and 2010. Hospital volume was stratified into tertiles (low, intermediate and high). Rates of major complications, failure t...
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#1Won Jun Kim (Korea University Medical Center)
#1Won Jun Kim (KU: Korea University)H-Index: 3
Last. Sungsoo Park (KU: Korea University)H-Index: 20
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Background: Acellular dermal matrix is a biologic material derived from the skin of human cadaveric donors. It has been used successfully in the past to reduce complications in breast surgery and hernia repair. This investigation was aimed at assessing the feasibility of using acellular dermal matrix to support the anastomosis after gastrectomy with the aim of reducing anastomotic site leakage complications. Methods: Patients were randomly assigned to standard anastomotic reconstruction (control...
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