Critical review on engineering deaminases for site-directed RNA editing
Abstract
The game-changing role of CRISPR/Cas for genome editing draw interest to programmable RNA-guided tools in general. Currently, we see a wave of papers pioneering the CRISPR/Cas system for RNA targeting, and applying them for site-directed RNA editing. Here, we exemplarily compare three recent RNA editing strategies that rely on three distinct RNA targeting mechanisms. We conclude that the CRISPR/Cas system seems not generally superior to other...
Paper Details
Title
Critical review on engineering deaminases for site-directed RNA editing
Published Date
Feb 1, 2019
Volume
55
Pages
74 - 80
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