Foam fractionation for the concentration of exopolysaccharides produced by repeated batch fermentation of cordyceps militaris

For improving the yield of exopolysaccharides (EPSs) produced by Cordyceps militaris and the efficiency of downstream separation technology, a combination technology of repeated batch fermentation and two-stage foam fractionation was designed. First, the suitable parameters of repeated batch fermentation (RBF) were determined. The results showed that the suitable broth replacement time point and replacement ratio were fifth day and 80% (v/v),...