Impact of Reduced Preincision Antibiotic Infusion Time on Surgical Site Infection Rates

Objective: Our objective was to determine the impact of total preincision infusion time on surgical site infections (SSIs) and establish an optimal time threshold for subsequent prospective study. Background: SSIs remain a major cause of morbidity. Although regulated, the total time of infusion of preincision antibiotics varies widely. Impact of infusion time on SSI risk is poorly understood. Methods: All consecutive patients (n = 46,791)...