Short Tetra‐peptide from soy‐protein hydrolysate attenuates hyperglycemia associated damages in H9c2 cells and ICR mice

Various novel therapeutic interventions are evaluated to overcome hypertrophy and apoptosis associated with diabetic cardiomyopathy. In this study, the anti-apoptotic and anti-hypertrophic efficiency of a short peptide composed of Val-His-Val-Val (VHVV) from a soy-protein hydrolysate was investigated against high glucose (HG) challenge. H9c2 cells were challenges with 33 mM of glucose and showed elevated levels of apoptotic events, pro-apoptotic...