P051 Low-level antibody against shared epitopes – are they relevant?

This case illustrates the importance of considering low-level antibody reactivity against HLA shared epitopes. A 58 year African American female patient with ESDR due to DM type 2 was evaluated for simultaneous kidney-pancreas transplantation. Although the patient had 4 pregnancies, based on the One Lambda Single Antigen (SA) results, the patient had only weak (<2000 MFI) antibodies against Cw4, DR53, and some DP antigens. The patient received...