Glutathione S-transferase P deficiency induces glucose intolerance via JNK-dependent enhancement of hepatic gluconeogenesis
Published on Nov 1, 2018in American Journal of Physiology-endocrinology and Metabolism4.13
· DOI :10.1152/ajpendo.00345.2017
Hepatic glutathione S-transferases (GSTs) are dysregulated in human obesity, nonalcoholic fatty liver disease, and diabetes. The multifunctional GST pi-isoform (GSTP) catalyzes the conjugation of g...