P055 To be a DSA or not to be a DSA, we need to know!

The accuracy of HLA antibody testing is very important for entering UNOS Unacceptable donor antigens, evaluating organ offers by virtual and prospective crossmatch, and evaluating donor specific antibodies (DSAs) pre and post transplant. It is known that Single Antigen Beads (SAB) often have problems with false positive reactions, when the manufacturing process results in 3–5% denatured HLA determinants on every bead, exposing cryptic, non HLA...