CRISPR-Cas guides the future of genetic engineering
Abstract
The diversity, modularity, and efficacy of CRISPR-Cas systems are driving a biotechnological revolution. RNA-guided Cas enzymes have been adopted as tools to manipulate the genomes of cultured cells, animals, and plants, accelerating the pace of fundamental research and enabling clinical and agricultural breakthroughs. We describe the basic mechanisms that set the CRISPR-Cas toolkit apart from other programmable gene-editing technologies,...
Paper Details
Title
CRISPR-Cas guides the future of genetic engineering
Published Date
Aug 31, 2018
Journal
Volume
361
Issue
6405
Pages
866 - 869
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