Research Progress in Understanding the Relationship Between Heme Oxygenase-1 and Intracerebral Hemorrhage
Abstract
Intracerebral hemorrhage (ICH) is a fatal acute cerebrovascular disease, with a high morbidity and mortality. Following ICH, erythrocytes release heme and several of its metabolites, thereby contributing to brain edema and secondary brain damage. Heme oxygenase is the initial and rate-limiting enzyme of heme catabolism, and the expression of heme oxygenase-1 (HO-1) is rapidly induced following acute brain injury. As HO-1 exerts it effects via...
Paper Details
Title
Research Progress in Understanding the Relationship Between Heme Oxygenase-1 and Intracerebral Hemorrhage
Published Date
Aug 20, 2018
Journal
Volume
9
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