In situ serial crystallography for rapid de novo membrane protein structure determination.
Abstract
De novo membrane protein structure determination is often limited by the availability of large crystals and the difficulties in obtaining accurate diffraction data for experimental phasing. Here we present a method that combines in situ serial crystallography with de novo phasing for fast, efficient membrane protein structure determination. The method enables systematic diffraction screening and rapid data collection from hundreds of...
Paper Details
Title
In situ serial crystallography for rapid de novo membrane protein structure determination.
Published Date
Aug 27, 2018
Journal
Volume
1
Issue
1
Pages
124 - 124
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