Metabolic high density lipoprotein particles in human obesity – A novel tool for the measurement of metabolic inflammation?

Aim: Metabolic inflammation evident in obesity likely contributes to increased cardiovascular risk. We recently demonstrated that saturated-fat induced obesity induces a pro-inflammatory HDL proteome in mice compared to monounsaturated-fat induced obesity. This study hypothesized that similar adverse changes in HDL proteomic composition and function would be observed in human...