Functional brain network centrality is related to APOE genotype in cognitively normal elderly
Abstract
Introduction Amyloid plaque deposition in the brain is an early pathological change in Alzheimer's disease (AD), causing disrupted synaptic connections. Brain network disruptions in AD have been demonstrated with eigenvector centrality (EC), a measure that identifies central regions within networks. Carrying an apolipoprotein (APOE)‐ε4 allele is a genetic risk for AD, associated with increased amyloid deposition. We studied whether APOE‐ε4...
Paper Details
Title
Functional brain network centrality is related to APOE genotype in cognitively normal elderly
Published Date
Aug 22, 2018
Journal
Volume
8
Issue
9
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