Tailoring Collagen to Engineer the Cellular Microenvironment

Volume: 13, Issue: 12, Pages: 1800140 - 1800140
Published: Sep 21, 2018
Abstract
Collagen is the most abundant protein in the extracellular matrix (ECM), and it can direct the behavior of the neighboring cells. By customizing properties of collagen, it is possible to control the cells that interact with it. Utilizing a bottom-up strategy, modular gene fragments are assembled and recombinantly processed to create collagen-mimetic variants that modulate proteolytic degradation, cell adhesion, and mechanical characteristics....
Paper Details
Title
Tailoring Collagen to Engineer the Cellular Microenvironment
Published Date
Sep 21, 2018
Volume
13
Issue
12
Pages
1800140 - 1800140
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