Potential Intended and Unintended Consequences of Recommending Initiation of Colorectal Cancer Screening at Age 45 Years

The new ACS recommendation to lower the CRC screening age to 45 years may result in both intended and unintended consequences. Before embarking on a major change in screening policy, further research is needed to identify the underlying CRC risk factors in younger adults and the potential benefits of screening in this population. In the meantime, we should focus efforts to improve screening and follow-up among adults aged ≥50 years, as well as...