Adverse Childhood Experiences and the Risk of Diabetes: Examining the Roles of Depressive Symptoms and Cardiometabolic Dysregulations in the Whitehall II Cohort Study

OBJECTIVE Adverse childhood experiences (ACEs) are associated with an increased risk of diabetes in adulthood. However, the potential mediating roles of depression and cardiometabolic dysregulations in this association are not clear. RESEARCH DESIGN AND METHODS Prospective data were from the Whitehall II cohort study, with the phase 5 assessment (1997–1999) serving as baseline (n = 5,093, age range = 44–68 years, 27.3% female). ACEs were...