Intracellular interleukin-32γ mediates antiviral activity of cytokines against hepatitis B virus
Abstract
Cytokines are involved in early host defense against pathogen infections. In particular, tumor necrosis factor (TNF) and interferon-gamma (IFN-γ) have critical functions in non-cytopathic elimination of hepatitis B virus (HBV) in hepatocytes. However, the molecular mechanisms and mediator molecules are largely unknown. Here we show that interleukin-32 (IL-32) is induced by TNF and IFN-γ in hepatocytes, and inhibits the replication of HBV by...
Paper Details
Title
Intracellular interleukin-32γ mediates antiviral activity of cytokines against hepatitis B virus
Published Date
Aug 16, 2018
Journal
Volume
9
Issue
1
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