Abstract 12324: Sestrin2 is an Essential Regulator of Cardiac AMPK Signaling During Ischemia

Published: Nov 26, 2013
Abstract
Background: A novel stress-inducible protein, sestrin2, has emerged as a mediator of AMP-activated Protein Kinase (AMPK) signaling pathway. AMPK is a pertinent stress-activated kinase shown to have substantial cardioprotective capabilities against myocardial ischemia/reperfusion (I/R) injury. The regulation of AMPK in the ischemic heart remains elusive and is critical to the development of new therapeutic strategies. We hypothesized that...
Paper Details
Title
Abstract 12324: Sestrin2 is an Essential Regulator of Cardiac AMPK Signaling During Ischemia
Published Date
Nov 26, 2013
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