Prediction of Real-World Drug Effectiveness Prelaunch: Case Study in Rheumatoid Arthritis

Background. Decision makers often need to assess the real-world effectiveness of new drugs prelaunch, when phase II/III randomized controlled trials (RCTs) but no other data are available. Objective. To develop a method to predict drug effectiveness prelaunch and to apply it in a case study in rheumatoid arthritis (RA). Methods. The approach 1) identifies a market-approved treatment ( S) currently used in a target population similar to that of...